
Phenylephrine
(Rescue Therapy)

Phenylephrine (Rescue Therapy)
Phenylephrine is a rescue therapy used to treat priapism — an erection lasting longer than 4 hours. It is a critical part of any injectable ED treatment protocol and may be prescribed for emergency use in patients using therapies such as Trimix, Bimix, or QuadMix.
How It Works
Phenylephrine is an alpha-adrenergic agonist that causes vasoconstriction. When injected into the penis, it constricts blood vessels to reduce blood inflow and relieve a prolonged erection. It is typically administered in a clinical setting but may be dispensed for home use.
Contraindications
- Severe cardiovascular disease
- Uncontrolled hypertension
- Hypersensitivity to phenylephrine or its components
Possible Side Effects
- Pain or burning at injection site
- Temporary increase in blood pressure
- Anxiety, tremors, or dizziness
- Rare: cardiac arrhythmia

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