BiMix, TriMix and Quadmix are administered as a penile self-injection and are typically considered to be a powerful class of anti-erectile dysfunction agents. While the components on their own, indicated for a vast number of very different conditions, the practice of bringing them together in concert to treat erectile dysfunction has become commonplace in sexual medicine and is now considered the go-to treatment when PDE5 (phosphodiesterase type5) inhibitors are contraindicated or patients are non-responsive to Viagra or Cialis.  

TriMix and QuadMix are a combination of three compounds that act together to stimulate the tissue in the penis to fill with blood and become erect. The three compounds (Papaverine, Phentolamine and Prostaglandin) are mixed together in a customized ratio and strength for an individual man’s use.